Rehabilitation is often overlooked for cancer patients, especially those with advanced diagnoses, resulting in increased pain, disability, and stress. Palliative and hospice care both aim to improve quality of life but are distinct in their approach. For effective cancer rehab, active collaboration between multidisciplinary professionals is imperative. Despite challenges, rehab can be integrated into end-of-life care, helping patients with terminal diagnoses to maintain function, relieve distressing symptoms, and cope with their condition.